Ginsenoside Immunomodulatory Functions in Skin Diseases: Mechanisms and Prospects

Ginsenosides, the primary bioactive constituents of Panax ginseng, exhibit diverse biological effects relevant to dermatology. This 27.3 KB Excel file, authored by Donglin Yuan and last updated in April 2026, summarizes their chemical composition and mechanisms against conditions like psoriasis and melanoma. The review details modulation of pathways such as NF-κB/NLRP3 and Nrf2/HO-1, while noting challenges in clinical translation.

Use Cases

• Literature review analysis based on summarized in vitro and in vivo study findings.
• Pathway mapping based on described signaling mechanisms like PI3K/Akt/mTOR/MAPK.
• Drug synergy investigation based on mentioned synergistic effects among ginsenoside metabolites.
• Clinical trial gap analysis based on identified challenges like low oral bioavailability.

Strengths

• File is small (27.3 KB), facilitating quick download and inspection.
• License is clearly defined as CC-BY-4.0, permitting reuse with attribution.
• Description provides specific disease targets (psoriasis, dermatitis, photoaging) and molecular pathways.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Data appears to be a literature summary table; primary experimental data is likely not included.

Provenance

Source

figshare

Collection Method

Likely contains a synthesized literature review table.

Time Range

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Freshness

Last updated 2026-04-22 05:45:56; freshness should be verified.

Geography

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