Impact of Chronic SSRI Administration on Mouse Memory, Lipids, and Membrane Properties

A 653.6 KB dataset from figshare, last updated on 2026-04-17, containing results from a study by Michał Szuwarzyński. It likely presents tabular data on the effects of fluoxetine and escitalopram on memory parameters, lipid composition, and membrane elasticity in C57Bl/6J mice, as measured by behavioral tests, FT-IR spectroscopy, and atomic force microscopy.

Use Cases

• Correlating changes in lipid composition with memory performance based on FT-IR spectroscopy data mentioned in the description
• Modeling the relationship between membrane elasticity and SSRI treatment based on atomic force microscopy measurements
• Comparing the differential effects of fluoxetine and escitalopram on spatial and working memory based on modified Barnes maze results

Strengths

• Dataset is licensed under CC-BY-4.0, allowing for open reuse and redistribution.
• The study design is described in detail, including specific drug doses (fluoxetine 10 mg/kg, escitalopram 2 mg/kg) and brain regions analyzed (prefrontal cortex, hippocampus, amygdala).

Limitations

• Row count and column-level documentation are unknown, which may limit suitability assessment.
• The data is contained in a 653.6 KB DOCX file, suggesting a limited scope and potentially requiring extraction from a document format.

Provenance

Source

figshare, author Michał Szuwarzyński

Collection Method

Data was generated from laboratory experiments on C57Bl/6J mice involving behavioral memory tests, Fourier Transform Infrared Spectroscopy (FT-IR), and atomic force microscopy.

Time Range

null

Freshness

Last updated 2026-04-17 05:21:47

Geography

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