Table 1_Impact of whole-herd vaccination on a caprine coxiellosis outbreak: a longitudinal

A longitudinal study investigating Coxiella burnetii dynamics and host microbiota after vaccination in goats following a Q fever outbreak. The dataset includes results from fecal, milk, vaginal, preputial, nasopharyngeal, environmental, and blood samples analyzed via qPCR, 16S rRNA sequencing, and serology. The research was authored by Raquel Toledo-Perona and published on figshare in June 2026.

Use Cases

• Modeling vaccine efficacy based on the reported 60% reduction in shedders after primary vaccination.
• Analyzing disease transmission dynamics based on data showing nasopharyngeal samples had the highest and most persistent positivity.
• Studying host-microbiota interactions in reproductive health based on reported significant shifts in microbial diversity across anatomical sites.
• Assessing the role of male animals in disease maintenance based on the first detection of C. burnetii in the buck prepuce.

Strengths

• Longitudinal design tracking animals over multiple kidding seasons, with seroconversion reaching approximately 90% by the third season.
• Multi-modal sample analysis covering serology, qPCR, and 16S rRNA metabarcoding across seven anatomical and environmental sample types.
• Reported statistically significant findings, such as a p<0.05 reduction in vaginal pathogen load.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The dataset is small (690.9 KB), indicating limited scope or aggregated summary data.

Provenance

Source

figshare

Collection Method

Longitudinal study analyzing biological samples from goats after a Q fever outbreak and vaccination campaign.

Freshness

Last updated 2026-06-03 13:33:49; freshness should be verified.