Table 1_In silico molecular docking and in vivo evidence of whey protein concentrate-media

Huda Fayez Al-Rashedi published this dataset on figshare in May 2026. It contains results from a study on whey protein concentrate's protective effects against chemically induced intestinal damage in male albino rats. The 25.5 KB Excel file includes data from molecular docking simulations and in vivo measurements of oxidative stress, inflammation, apoptosis, and fibrosis markers.

Use Cases

• Validate molecular docking predictions of peptide binding with TGF-β and Keap1 based on the described in silico study.
• Analyze correlations between oxidative stress markers (nitric oxide, malondialdehyde, glutathione) and tissue damage outcomes.
• Model the dose-response relationship of whey protein concentrate pretreatment on apoptotic markers (Bcl-2, Bax) and inflammatory indicators (IL-1β, TNF-α).
• Investigate gene expression patterns for ZO-1 and HO-1 in intestinal tissue under toxic insult and treatment.

Strengths

• Dataset includes both in silico molecular docking results and in vivo experimental data from a controlled animal study.
• Experimental design involved 40 rats across four treatment groups, with treatments administered 5 days per week over 3 weeks.
• License is CC-BY-4.0, permitting broad reuse and sharing.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The dataset is small (25.5 KB), indicating limited scope and likely a summary of results rather than raw individual measurements.

Provenance

Source

Huda Fayez Al-Rashedi

Collection Method

Data likely originates from a controlled laboratory experiment involving 40 male albino rats and molecular docking simulations.

Freshness

Last updated 2026-05-13 05:53:57; freshness should be verified.