Mouse Lung Macrophage Response to Scutellaria Barbata Extract

Experimental data validates the bi-directional immune modulatory effect of Scutellaria barbata D. Don extract on lung macrophages in a mouse model. The dataset contains results from in vivo evaluation studies exploring the plant extract's material basis. Kerui Wu authored this work, which was last updated in April 2026.

Use Cases

• Analyze macrophage proinflammatory polarization states with and without LPS stimulation to quantify bi-directional modulation.
• Correlate specific chemical components from the material basis analysis with observed immune response metrics.
• Model the therapeutic window for Scutellaria barbata extract based on dose-response data from the in vivo evaluation.

Strengths

• Data underpins a peer-reviewed study validating a novel bi-directional immune modulation concept.
• Published under a permissive CC-BY-4.0 license allowing reuse and redistribution.

Limitations

• Dataset scale is limited at 1.6 MB, suggesting a constrained sample size or limited feature set.
• Specific row counts, column names, and sample data are unavailable, hindering immediate technical assessment.

Provenance

Source

Kerui Wu via figshare.

Collection Method

In vivo experimental evaluation using a mouse model, likely involving flow cytometry or immunohistochemistry for macrophage analysis.

Time Range

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Freshness

Last updated in April 2026.

Geography

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