Meta-Analysis of Fertility Concerns in Cancer Patients, 13 Studies

A systematic review and meta-analysis of 13 studies published up to August 2024, including data from 3,282 cancer patients. The work, authored by Yaxin Wang, identifies and quantifies factors associated with fertility concerns, such as depression, education level, and treatment type. Results were synthesized using RevMan 5.4 and Stata 17.0 software.

Use Cases

• Identifying risk factors for fertility distress based on patient demographics like education level and marital status.
• Investigating the clinical paradox of reproductive counseling potentially increasing fertility concerns.
• Analyzing the association between specific cancer treatments, such as endocrine therapy, and psychological outcomes.
• Supporting the development of targeted clinical interventions based on quantified odds ratios for various factors.

Strengths

• Includes data from 3,282 patients across 13 studies.
• Provides specific odds ratios and confidence intervals for 8 distinct influencing factors.
• Follows a registered systematic review protocol (PROSPERO CRD42024582238).

Limitations

• The dataset is a 15.9 KB DOCX document; the underlying structured data (rows/columns) is unavailable.
• Column-level documentation is absent; field semantics must be inferred from the manuscript text.
• Row count is unknown, which may limit suitability assessment for quantitative analysis.

Provenance

Source

Systematic search of PubMed, Web of Science, Embase, Cochrane Library, and Scopus.

Collection Method

Meta-analysis of 11 cross-sectional and 2 longitudinal studies.

Time Range

Literature search from database inception through August 2024.

Freshness

Last updated 2026-05-18 11:24:27; freshness should be verified.