Brucellosis Outbreak Transmission Networks in Shandong, China, 2023

26 related cases were identified in a 2023 brucellosis outbreak in Shandong Province, China. The dataset integrates epidemiological investigation with whole-genome sequencing of 10 isolated Brucella strains to reconstruct transmission chains. It was created by Chanjuan Huangfu and published on figshare under a CC-BY-4.0 license.

Use Cases

• Reconstructing disease transmission networks based on integrated epidemiological and genomic data.
• Analyzing pathogen lineage co-circulation based on core-genome SNP and MLVA typing results.
• Evaluating the concordance between molecular and epidemiological links for outbreak cases.
• Studying the role of livestock trade networks in regional disease spread.

Strengths

• Integrates two data types: epidemiological case data for 26 individuals and genomic data for 10 isolated strains.
• Provides high-resolution molecular typing results, including cgSNP analysis showing a clonal cluster with 0 SNP difference.
• Includes a specific measure of data integration success, with molecular-epidemiological concordance confirmed for 38.5% (10/26) of cases.

Limitations

• The dataset is very small at 15.7 KB, indicating limited scope.
• Row count and column-level documentation are unknown, which may limit suitability assessment.
• Epidemiological data was missing or isolates were not recovered for 61.5% of cases, preventing definitive transmission links.

Provenance

Source

figshare, author Chanjuan Huangfu.

Collection Method

Data gathered through field epidemiological investigations, active case finding, retrospective data review, and laboratory analysis including bacterial culture and whole-genome sequencing.

Time Range

Outbreak investigated in 2023, with an index case from 2022.

Freshness

Last updated 2026-04-21 04:11:05; freshness should be verified.

Geography

Shandong Province, China, affecting multiple villages.