Clinical Data on Vitamin D, Ferritin, and Eosinophils in 120 Children with Asthma

A retrospective study of 120 children with asthma, comprising 60 with acute exacerbation and 60 in clinical remission, conducted by Pingping Wang. The dataset includes measurements of serum 25-hydroxyvitamin D, ferritin, interleukin-6, and eosinophil-related indices, with results last updated in April 2026.

Use Cases

• Predicting acute asthma exacerbation risk in children based on ferritin and eosinophil percentage levels.
• Analyzing the dose-response relationship between vitamin D levels and exacerbation risk using restricted cubic spline methods.
• Building a combined predictive model incorporating ferritin, eosinophil percentage, and vitamin D, as described in the study.
• Investigating potential interactions between metabolic (vitamin D, ferritin) and inflammatory (eosinophils, IL-6) pathways in asthma.

Strengths

• Includes specific median and mean values for key biomarkers (e.g., ferritin 145 vs. 82 ng/mL, vitamin D 18.6 vs. 24.3 ng/mL).
• Reports statistical results from multivariable logistic regression (ORs, CIs) and model discrimination (AUC = 0.973).
• Data is openly licensed under CC-BY-4.0.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The study notes a risk of overfitting in the combined model and limited interaction testing due to sample size.

Provenance

Source

Pingping Wang, via figshare.

Collection Method

Single-center retrospective study with clinical measurements.

Time Range

The study period is not specified.

Freshness

Last updated 2026-04-20 04:13:29; freshness should be verified.

Geography

The geographic location of the single center is not specified.