Dual-Control Model of Prefrontal Cortex Modularity: A Review Document

A 19.1 KB document by Tetsuo Yamamori, last updated in June 2026, synthesizes neuroanatomical frameworks with spatial transcriptomics and connectomics. It proposes a 'Dual-Control Model' for the intrinsic elaboration of primate prefrontal cortex modularity. The document is available under a CC-BY-4.0 license on figshare.

Use Cases

• Reviewing the proposed 'Dual-Control Model' of axon bundling and synaptic docking for PFC circuit assembly.
• Comparing PFC development with map-driven visual, point-driven olfactory, and layer-driven hippocampal systems as described.
• Studying the role of specific molecular families (e.g., ephrin/Eph, PCDH, ROBO2, CBLN2, cadherins) in cortical connectivity.
• Investigating the hypothesis linking outer subventricular zone expansion and whole-genome duplication to PFC modularity.

Strengths

• Document is under a permissive CC-BY-4.0 license, allowing for broad reuse.
• The description provides a detailed theoretical framework synthesizing multiple fields of neuroscience.
• Last update timestamp is precisely recorded as 2026-06-02 05:26:57.

Limitations

• The dataset is a 19.1 KB DOCX file, indicating a very limited textual scope, likely a review article.
• Row count and column-level documentation are absent; the content structure must be inspected after download.
• The description is theoretical; it does not indicate the presence of primary numerical or structured data for analysis.

Provenance

Source

Tetsuo Yamamori via figshare.

Collection Method

Likely a literature review and synthesis of existing anatomical tracer, spatial transcriptomic, and connectomic data.

Freshness

Last updated 2026-06-02 05:26:57.