IR-780 Treatment Effects on Bladder Function in Rats with Partial Outlet Obstruction

A figshare-hosted research document by Feng Pi, last updated March 18, 2026, details a study on IR-780 treatment in a rat model of partial bladder outlet obstruction. The 36.0 KB document describes experimental results, including bladder pressure measurements, tissue staining, and protein expression analysis. It investigates the compound's effects on urinary function, smooth muscle cell apoptosis, and oxidative stress pathways.

Use Cases

• Analyzing the efficacy of IR-780 treatment based on bladder pressure measurement results described in the study.
• Studying mitochondrial protection mechanisms based on reactive oxygen species levels and protein expression data mentioned.
• Modeling pathological changes in bladder smooth muscle tissue based on the described histological and electron microscopy findings.

Strengths

• Document is under a CC-BY-4.0 license, permitting broad reuse.
• Specific experimental details are provided, including group sizes (eight rats per group) and dosage (0.667 mg/kg).
• Last update timestamp is precise: 2026-03-18 07:43:56.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is very small at 36.0 KB, indicating limited raw data scope.

Provenance

Source

figshare, author Feng Pi.

Collection Method

Data appears to be generated from a controlled laboratory study using a rat model of partial bladder outlet obstruction.

Freshness

Last updated 2026-03-18 07:43:56; freshness should be verified.