Mild Cortisol Secretion and Muscle Strength in Adrenal Incidentaloma Patients

Martina Romanisio's study compares muscle health, body composition, and quality of life in 62 participants: 21 with mild autonomous cortisol secretion (MACS), 21 with non-functioning adrenal adenomas (NFAA), and 20 healthy controls. Data includes handgrip dynamometry, sit-to-stand tests, MRC scale scores, bioelectrical impedance analysis, and EQ-5D/SARC-F questionnaires. The dataset was last updated on 2026-04-30.

Use Cases

• Compare muscle strength metrics between patient groups based on handgrip dynamometry and sit-to-stand test results.
• Analyze associations between cortisol levels and musculoskeletal health based on MRC scale scores and post-dexamethasone suppression test cortisol concentrations.
• Investigate body composition differences using bioelectrical impedance analysis data for fat-free mass, muscle mass, and fat mass.
• Assess quality of life impact in MACS patients based on EQ-5D and SARC-F questionnaire scores.

Strengths

• Includes data from 62 participants across three distinct clinical groups (MACS, NFAA, healthy controls).
• Assesses multiple dimensions of health: muscle strength via three methods, body composition via BIA, and quality of life via two questionnaires.
• License is CC-BY-4.0, permitting broad reuse with attribution.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is small in scale (683.1 KB), indicating a limited sample size.

Provenance

Source

Martina Romanisio via figshare

Collection Method

Clinical study enrolling 62 participants and assessing them with dynamometry, physical tests, bioelectrical impedance analysis, and questionnaires.

Freshness

Last updated 2026-04-30 04:17:19; freshness should be verified.