FMD Antibody Kinetics in Cattle Vaccinated with Combined Vaccine

A 365-day study of antibody kinetics in cattle vaccinated against foot-and-mouth disease, hemorrhagic septicemia, and black quarter. Thirty cattle were allocated into groups with different vaccination histories and booster schedules, and blood samples were collected at five intervals post-vaccination. The dataset was created by Rajeev Ranjan and published on figshare under a CC-BY-4.0 license.

Use Cases

• Model antibody decay curves based on booster vaccination status mentioned in the description
• Compare immune response between naive calves and adult cattle with unknown vaccination history
• Evaluate the economic impact of combined vaccination strategies at wildlife-livestock interfaces
• Analyze the correlation between ELISA and virus neutralization test results for protective antibodies

Strengths

• Data covers a longitudinal study with measurements at five specific time points (days 0, 28, 120, 240, and 365)
• Experimental design includes three distinct cattle groups with controlled booster schedules
• Results are validated by two assay methods (solid-phase competitive ELISA and virus neutralization testing)

Limitations

• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment
• The dataset is very small (161.0 KB), indicating limited scope or detail

Provenance

Source

Rajeev Ranjan

Collection Method

Blood samples collected from cattle in a field study, with antibody levels measured via ELISA and virus neutralization testing.

Time Range

Study period covers 365 days post-vaccination.

Freshness

Last updated 2026-05-22 04:28:00; freshness should be verified