Rabbit Rotator Cuff Tear Lactylation Proteomics with 2,624 Modification Sites

A proteomics study by Tong Pan, uploaded to figshare in March 2026, investigates lactylation modifications in rabbit rotator cuff tear samples. The dataset identifies 2,624 modification sites on 851 proteins, with results on subcellular localization, differentially modified proteins, and functional pathway enrichment. The work aims to provide new therapeutic insights for musculoskeletal injuries.

Use Cases

• Identify potential therapeutic targets based on differentially modified proteins in rotator cuff tears.
• Analyze functional pathway enrichment of lactylated proteins in RNA, DNA, and cellular metabolism processes.
• Study the subcellular localization patterns of lactylation modifications in cytoplasm, mitochondria, and nucleus.
• Investigate the proposed 'lysine co-lactylation modification effect' concept based on motif analysis.

Strengths

• Contains 2,624 identified lactylation modification sites on 851 proteins.
• Includes results for subcellular localization, differential modification, and functional enrichment analysis.
• Released under a permissive CC-BY-4.0 license for reuse.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The dataset is very small at 25.4 KB, indicating limited scope.

Provenance

Source

figshare, author Tong Pan.

Collection Method

Lactylation omics conducted on rabbit rotator cuff tear samples.

Time Range

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Freshness

Last updated 2026-03-17 15:04:59; freshness should be verified.

Geography

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