IVF Embryo Ploidy Outcomes with LH Supplementation Analysis, 2018-2024

A retrospective single-center cohort study from January 2018 to January 2024 analyzed 4,417 IVF/PGT-A cycles. After propensity score matching, 952 cycles (476 with FSH-only and 476 with added LH activity) were compared for embryo euploidy rates and reproductive outcomes. The dataset likely contains clinical metrics such as euploidy rate, oocyte yield, and pregnancy outcomes.

Use Cases

• Compare embryo euploidy rates based on gonadotropin stimulation protocols mentioned in the description
• Analyze the relationship between female age and embryo ploidy status using the odds ratio reported
• Evaluate clinical pregnancy and live birth outcomes following frozen euploid embryo transfer (FEET)
• Study the effect of embryo quality (good vs. poor) on ploidy odds using the provided odds ratio

Strengths

• Dataset covers 4,417 IVF/PGT-A cycles from a six-year period (2018-2024)
• Analysis uses 1:1 propensity score matching on female age and oocyte yield for 952 matched cycles
• Primary outcome assessed via trophectoderm biopsy and next-generation sequencing

Limitations

• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment
• Data is from a single-center study, which may limit generalizability

Provenance

Source

figshare, authored by Merve Dizdar

Collection Method

Retrospective single-center cohort study

Time Range

January 2018–January 2024

Freshness

Last updated 2026-05-22 04:30:18; freshness should be verified