Table 1_Ligature-induced periodontitis in mice potentially accelerates CD4+ T-cell senesce

Experimental data from a study investigating the link between periodontitis and rheumatoid arthritis in mice. The dataset includes results from BALB/c mice aged 5–42 weeks, with analyses of CD4+ T-cell senescence markers, cytokine levels, and RNA-seq data. The work was authored by Jinfeng Li and last updated on 2026-05-26.

Use Cases

• Analyze the relationship between ligature-induced periodontitis and T-cell senescence markers like PD-1 and CD153.
• Investigate senescence-associated secretory phenotype (SASP) cytokine levels in a mouse model of rheumatoid arthritis.
• Study differentially expressed genes related to senescence from the provided RNA-seq analysis.
• Model the exacerbation of collagen antibody-induced arthritis (CAIA) via adoptive T-cell transfer.

Strengths

• Data is derived from a controlled experimental model using BALB/c mice across a defined age range of 5–42 weeks.
• Includes multiple analytical layers: flow cytometry for cell markers, cytokine assays, RNA-seq, and in vivo disease modeling.
• Dataset is openly shared under a CC-BY-4.0 license, facilitating reuse.

Limitations

• The dataset is very small at 14.7 KB, indicating limited scope or summary-level data.
• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment for large-scale analyses.

Provenance

Source

figshare

Collection Method

Experimental data from a laboratory study involving mouse models, cell isolation, stimulation, and RNA sequencing.

Freshness

Last updated 2026-05-26 06:03:40; freshness should be verified.