Liubao Tea Multi-Omics Analysis: Modulation of Lymphatic Endothelial Cell Metabolism

A multi-omics dataset from a study investigating Liubao tea as a functional fermented food. The data includes results from single-cell transcriptomics, bulk transcriptomics, network pharmacology, and molecular docking analyses, along with in vitro experimental validation on human lymphatic endothelial cells. The dataset was authored by Xiaoxiao Huang and last updated on 2026-05-18.

Use Cases

• Identify potential therapeutic targets for lymphatic diseases based on multi-omics integration analysis described in the study.
• Validate molecular docking predictions for natural product compounds, such as tirilose, against protein targets like PRKCB.
• Analyze the effects of fermented tea extracts on cell survival and migration rates based on CCK-8 and wound healing assay results.
• Investigate gene expression changes (e.g., PRKCB, PROX1) in lymphatic endothelial cells under inflammatory conditions.

Strengths

• Integrates multiple analysis methods: single-cell transcriptomics, bulk transcriptomics, network pharmacology, and molecular docking.
• Includes specific, validated experimental results, such as a PRKCB fold change of 24.30 and a binding energy of -9.3 kcal/mole for tirilose.
• Released under a permissive CC-BY-4.0 license, facilitating reuse.

Limitations

• Row count and column-level documentation are unknown, requiring manual inspection after download.
• The dataset is very small (11.0 KB), suggesting it likely contains summary results rather than raw omics data.
• The description is detailed but does not specify the exact table contents or data structure.

Provenance

Source

figshare

Collection Method

Combined computational multi-omics analysis and in vitro cell culture experiments.

Time Range

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Freshness

Last updated 2026-05-18 05:38:43; freshness should be verified.

Geography

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