Lobetyolin Effects on PCOS Mouse Model Gut Microbiota and Bile Acid Data

A 28-day study of lobetyolin (LT) administered to DHEA-induced PCOS mice. The dataset likely contains hormone levels, glucose tolerance, estrus cycle, gut microbiota sequencing, bile acid metabolomics, and inflammatory marker measurements. It was authored by Lijuan Li and last updated on May 1, 2026.

Use Cases

• Analyze correlations between gut microbiota composition and serum androgen levels based on 16S rRNA sequencing and hormone assays.
• Model the relationship between bile acid metabolite levels and insulin sensitivity based on metabolomics and glucose tolerance data.
• Investigate molecular pathways linking inflammation to endometrial dysfunction based on cytokine and uterine marker expression data.

Strengths

• Data includes multiple biological endpoints: hormone levels, microbiota sequencing, bile acid metabolomics, and inflammatory markers.
• The study design includes a 28-day longitudinal intervention period.
• The dataset is openly licensed under CC-BY-4.0.

Limitations

• The dataset is very small (14.7 KB), indicating limited scope or summary-level data.
• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.

Provenance

Source

figshare

Collection Method

Data generated from a DHEA-induced PCOS murine model experiment with lobetyolin intervention.

Freshness

Last updated 2026-05-01 05:27:38; freshness should be verified.