Long-term Trends in Leukemia Subtype Burden in China, 1990-2021

GBD 2021 data provides estimates for four major leukemia subtypes in China from 1990 to 2021. The dataset includes 105,670 estimated new cases in 2021 and tracks incidence, deaths, and disability-adjusted life years (DALYs) for acute myeloid leukemia (AML), chronic myeloid leukemia (CML), acute lymphoblastic leukemia (ALL), and chronic lymphocytic leukemia (CLL). Author Yudi Shangguan published this analysis on figshare under a CC-BY-4.0 license.

Use Cases

• Analyze long-term incidence trends for leukemia subtypes based on age-standardized rates from 1990 to 2021.
• Project future leukemia subtype incidence rates through 2046 based on Bayesian age-period-cohort modeling.
• Compare the burden of acute lymphoblastic leukemia (ALL) and chronic lymphocytic leukemia (CLL) based on distinct age and cohort patterns.
• Assess contributions of risk factors like smoking and high body-mass index to leukemia disability-adjusted life years (DALYs).
• Evaluate public health interventions by studying subtype-specific declines in incidence and mortality for AML and CML.

Strengths

• Data spans a 32-year period from 1990 to 2021, enabling long-term trend analysis.
• Analysis is stratified by age and sex, allowing for demographic-specific insights.
• Includes projections for incidence rates up to 2046, providing forward-looking utility.
• Covers four distinct leukemia subtypes (AML, CML, ALL, CLL) with separate trend assessments.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is a 19.7 KB DOCX file, suggesting it contains summary tables or analysis text rather than raw, row-level data.
• Row count is unknown, which may limit suitability assessment for large-scale statistical modeling.

Provenance

Source

Global Burden of Disease (GBD) 2021 database.

Collection Method

Joinpoint regression, age-period-cohort (APC) modeling, and Bayesian APC modeling applied to GBD estimates.

Time Range

1990 to 2021, with projections to 2046.

Freshness

Last updated 2026-06-04 04:32:10; freshness should be verified.

Geography

China.