Rab44 Knockout Mouse Data on Ovalbumin-Induced Allergic Airway Inflammation

Experimental data from a study investigating the role of Rab44 in a murine model of allergic airway inflammation. The dataset includes results from histopathology, RNA sequencing, degranulation assays, and flow cytometry comparing Rab44-knockout and wild-type mice. It was authored by Haruka Mawatari and last updated in May 2026.

Use Cases

• Analyze differential gene expression based on RNA-seq results from knockout versus wild-type mice.
• Compare immune cell infiltration levels based on counts of lymphocytes, monocytes, and eosinophils in bronchoalveolar lavage fluid.
• Investigate eosinophil function based on assays measuring degranulation, adhesion, and chemotaxis.
• Study signaling pathways involved in immune and inflammatory responses based on RNA-seq pathway analysis.

Strengths

• Dataset is 8.0 MB in size, indicating a focused and manageable experimental dataset.
• Includes results from multiple experimental methods: RNA-seq, histopathology, flow cytometry, and functional assays.
• Data is associated with a specific, peer-reviewed research hypothesis on Rab44's role in asthma.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment for certain analyses.
• Data is derived from a single, controlled mouse model study, limiting generalizability.

Provenance

Source

figshare

Collection Method

Data generated from laboratory experiments on Rab44-knockout and wild-type mice sensitized to ovalbumin.

Freshness

Last updated 2026-05-21 05:44:24; freshness should be verified.