EPHB4 RNA Modification Data for Gastric Cancer Lymphatic Metastasis Study

A 42.2 KB DOCX file authored by Yi Zhang and last updated on 2026-05-19. The document presents research data on the cooperative stabilization of EPHB4 mRNA by m5C and m6A modifications, linking it to lymphatic metastasis in gastric cancer. The study integrated transcriptome sequencing, bioinformatic analyses, and in vitro/in vivo functional assays.

Use Cases

• Study the role of EPHB4 in cancer metastasis based on transcriptome sequencing data mentioned in the description
• Investigate m5C and m6A RNA modification crosstalk based on the described NSUN2/YBX1 and IGF2BP1 mechanisms
• Validate epitranscriptomic markers for lymphatic metastasis prediction based on the described association with poor clinical outcome
• Identify potential therapeutic targets based on the described NSUN2-YBX1-IGF2BP1-EPHB4 axis

Strengths

• Data is associated with a specific, detailed biological mechanism described in the research document.
• The dataset is shared under a CC-BY-4.0 license, permitting reuse with attribution.

Limitations

• The dataset is a 42.2 KB DOCX file, indicating a very limited data scope, likely a summary table.
• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.

Provenance

Source

figshare, author Yi Zhang

Collection Method

Likely contains summarized results from integrated transcriptome sequencing, bioinformatic database analyses, and immunohistochemical validation.

Freshness

Last updated 2026-05-19 22:01:30; freshness should be verified.