Myasthenia Gravis Patient Speech Acoustic Metrics and Clinical Scores

A single-center cross-sectional study of 17 adults with confirmed myasthenia gravis. The dataset contains acoustic metrics from voice recordings and contemporaneous clinical assessment scores, published by Aurora Zanghì in May 2026. Recordings include sustained vowels, standardized reading, and spontaneous speech, with metrics for intensity and fundamental frequency.

Use Cases

• Identify acoustic markers of bulbar dysfunction based on connected-speech intensity decrements.
• Investigate sex-related differences in speech patterns based on the reported intensity reductions in male participants.
• Explore correlations between acoustic metrics and patient-reported outcomes like MG-ADL and rMG-QOL15 scores.
• Validate load-dependent speech alterations as a potential subclinical diagnostic tool.

Strengths

• Includes data from 17 consecutively enrolled patients with confirmed myasthenia gravis.
• Pairs standardized voice recordings with two contemporaneous clinical assessments (MG-ADL and rMG-QOL15).
• Acoustic metrics are specified, including root-mean-square intensity (dB) and fundamental frequency (Hz).

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The cohort size of 17 patients is small, as noted in the study's conclusion.

Provenance

Source

figshare, authored by Aurora Zanghì.

Collection Method

Cross-sectional study of consecutively enrolled adults at a single center, involving standardized voice recordings and clinical assessments.

Freshness

Last updated 2026-05-19 04:21:07; freshness should be verified.