Maternal Vitamin Trajectories and Infant Birth Weight in a Pregnancy Trial

A secondary analysis of the Exercise Training in Pregnancy Trial (ETIP) study, including 57 mother-infant pairs with overweight or obesity. Plasma and serum measurements of vitamins A, D, and E were taken during the second and third trimesters and analyzed for associations with infant birth weight. The dataset was authored by Astrid Kamilla Stunes and last updated on 2026-04-15.

Use Cases

• Analyze longitudinal changes in maternal vitamin concentrations based on trimester-specific measurements.
• Investigate associations between maternal vitamin status and infant birth weight categories (normal vs. macrosomic).
• Examine the prevalence of vitamin insufficiency/deficiency in a cohort with overweight or obesity.
• Model potential interactions between vitamins A and D on fetal growth outcomes.

Strengths

• Includes specific mean and SD values for vitamin concentrations across trimesters (e.g., retinol declined from 1.52 to 1.32 µmol/L).
• Reports prevalence rates for clinical conditions (19.3% vitamin A insufficiency, 43.9% macrosomia).
• Data is derived from a structured clinical trial with defined measurement methods (HPLC, LC-MS/MS).

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is very small (14.7 KB), indicating limited scope and sample size (57 pairs).

Provenance

Source

Secondary analysis of the Exercise Training in Pregnancy Trial (ETIP) study.

Collection Method

Plasma and serum samples analyzed via high performance liquid chromatography and liquid chromatography-tandem mass spectrometry.

Time Range

Measurements taken during the second and third trimesters of pregnancy.

Freshness

Last updated 2026-04-15 04:37:06; freshness should be verified.

Geography

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