Maternal Serum Ferritin and SGA Risk from Shanghai Cohort, 2018-2020

A longitudinal cohort study of 17,451 pregnant women delivering at Shanghai First Maternity and Infant Hospital between 2018 and 2020. It investigates the association between maternal serum ferritin levels measured at two gestational windows and the risk of small-for-gestational-age births. The dataset was authored by Nana Guo and is available under a CC-BY-4.0 license.

Use Cases

• Analyze the dose-response relationship between serum ferritin levels and SGA risk based on the reported threshold of 12.1 ng/ml.
• Model the risk of SGA based on trimester-specific ferritin categories (low, medium, high) using the logistic regression results.
• Investigate nonlinear associations between biomarkers and birth outcomes using the restricted cubic spline method described.
• Compare SGA incidence rates between groups with elevated (≥18.1 ng/mL) and lower serum ferritin levels in the third trimester.

Strengths

• Includes 17,451 pregnant women, providing a substantial sample size.
• Serum ferritin levels were measured at two specific gestational windows (8.0–13.6 weeks and 29.0–31.6 weeks), enabling longitudinal analysis.
• Results include specific odds ratios and confidence intervals (e.g., aOR = 1.418, 95% CI: 1.089–1.846) for risk assessment.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Data reflects a single-hospital cohort in Shanghai, which may introduce geographic bias.

Provenance

Source

Electronic medical records from Shanghai First Maternity and Infant Hospital.

Collection Method

Clinical measurements and binary logistic regression analysis.

Time Range

2018 to 2020

Freshness

Last updated 2026-04-24 04:23:01; freshness should be verified.

Geography

Shanghai, China