Maternal Thyroid Hormone Changes and Preeclampsia Risk in Euthyroid Women

A retrospective study investigates associations between thyroid hormone level changes during pregnancy and preeclampsia risk. The dataset likely contains maternal TSH and FT4 measurements from early and late pregnancy, along with pregnancy outcomes. It was authored by Jianxia Lin and last updated on 2026-05-26.

Use Cases

• Modeling nonlinear risk associations for preeclampsia based on TSH changes.
• Assessing the impact of thyroid function decompensation on preterm birth and low birth weight.
• Calculating population-attributable risk for severe preeclampsia cases.
• Performing sensitivity analyses on clinical risk factor models.

Strengths

• Analysis includes a specific risk threshold for TSH change (0.68 mIU/L).
• Findings report adjusted odds ratios for complications, such as aOR=1.89 for preeclampsia.
• Results include population-attributable risk percentages (21.6% for preeclampsia cases).

Limitations

• Description metadata is limited; actual data quality requires manual inspection after download.
• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.

Provenance

Source

figshare

Collection Method

Retrospective study using logistic regression and restricted cubic spline models.

Freshness

Last updated 2026-05-26 04:39:18; freshness should be verified.