Neuropathic POTS Treatment Response Data from a Single-Center Retrospective Review

A single-center retrospective review identified 382 patients diagnosed with Postural Orthostatic Tachycardia Syndrome (POTS) between 2018 and 2020. The dataset, authored by Ryan G. Rilinger, compares treatment response durations between neuropathic and non-neuropathic POTS subtypes, with a key finding on ivabradine.

Use Cases

• Modeling treatment failure risk based on POTS subtype and medication type mentioned in the description.
• Identifying clinical variables predictive of neuropathic POTS based on the logistic regression analysis described.
• Comparing Kaplan-Meier survival curves for treatment response duration between patient subgroups.
• Validating the association between elevated baseline heart rate and neuropathic POTS subtype noted in the results.

Strengths

• Includes data from 382 diagnosed patients, providing a specific cohort size.
• Reports a key quantitative finding: a median treatment response duration of 26.7 months for neuropathic POTS patients on ivabradine.
• Uses established diagnostic tests (head-up tilt table, skin biopsy, quantitative sudomotor axon reflex test) as described in the methods.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is very small at 15.0 KB, indicating limited scope.

Provenance

Source

figshare

Collection Method

Single-center retrospective review of patient records.

Time Range

2018-2020

Freshness

Last updated 2026-05-26 05:25:56; freshness should be verified.