Cancer Phosphoproteomic Analysis of Tau Protein Phosphorylation Sites

An integrative analysis of human cellular phosphoproteomics datasets examines Tau phosphorylation beyond its canonical neuronal roles. The dataset, authored by Tejaswini Rohinath Poojari and last updated in May 2026, likely contains phosphosite-specific data for Tau and co-regulated proteins. It reveals Tau phosphosites such as S519, S713, S717, and S721 across various experimental conditions.

Use Cases

• Analyze Tau phosphorylation site co-regulation patterns based on phosphosite-specific functions mentioned in the description
• Identify upstream kinases involved in DNA damage response based on kinases like CDK12/13/14/16, GSK3B, RPS6KA3, and CSNK1E
• Study cancer-related processes such as DNA repair, cell motility, and cell growth based on inferred functional roles from co-regulation patterns
• Investigate coordinated phosphorylation within Tau based on mutual regulation among sites S713, S717, and S721

Strengths

• Dataset is licensed under CC-BY-4.0, allowing for open reuse and redistribution
• File size is 1.0 MB, indicating a manageable download and processing scale

Limitations

• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment for large-scale analyses

Provenance

Source

figshare

Collection Method

Integrative analysis of human cellular phosphoproteomics datasets

Freshness

Last updated 2026-05-22 04:27:59; freshness should be verified