Case Report: Microbiological Eradication of XDR Acinetobacter baumannii Infection

A single clinical case report details the treatment of a 63-year-old male with Stage IV cancer and neuromuscular disease who developed concurrent pulmonary and intra-abdominal infections with extensively drug-resistant Acinetobacter baumannii and Pseudomonas aeruginosa. The report, authored by Lei Yu and shared on figshare under a CC-BY-4.0 license, describes the use of sulbactam-durlobactam combined with imipenem-cilastatin after initial therapy failed. Microbiological cure was achieved within 14 days, though the patient ultimately succumbed to multiple organ dysfunction syndrome.

Use Cases

• Analyze clinical outcomes of novel antibiotic combinations based on the detailed patient history and treatment regimen described.
• Study the disconnect between microbiological and clinical success in critically ill patients based on the case's conclusion.
• Investigate treatment protocols for complicated intra-abdominal infections caused by carbapenem-resistant Acinetobacter baumannii based on the reported therapeutic approach.

Strengths

• Provides a detailed, real-world clinical narrative including patient comorbidities, treatment timeline, and specific microbiological results.
• Shared under a permissive CC-BY-4.0 license, allowing for reuse and redistribution.

Limitations

• Dataset is a single case report (15.8 KB DOCX file), representing an extremely limited sample size of n=1.
• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.

Provenance

Source

figshare

Collection Method

Clinical case report authored by Lei Yu.

Freshness

Last updated 2026-05-15 04:21:41; freshness should be verified.