Table 1_Microbiome–mycotoxin interactions and probiotic strategies: implications for gut h

A 2016–2025 review synthesizes mechanistic studies on how mycotoxins like aflatoxin B₁ and deoxynivalenol disrupt gut health and cancer pathways. Alice N. Mafe authored this structured, hypothesis-driven narrative review, examining microbial detoxification enzymes and probiotic interventions. The 15.4 KB document, last updated in March 2026, provides an integrated framework linking microbial mechanisms to health risks.

Use Cases

• Identify key microbial enzymes for detoxification based on the review of de-epoxidases, lactonases, and reductases.
• Analyze probiotic strain-specific effects based on the discussion of competitive exclusion, toxin binding, and anti-inflammatory actions.
• Study dysbiosis impacts on cancer pathways based on the review of NF-κB, STAT3, and IL-6 modulation.
• Evaluate strategies to mitigate epithelial barrier damage based on the synthesis of probiotic interventions and barrier function.

Strengths

• Focuses on recent mechanistic studies from 2016 to 2025, providing a contemporary synthesis.
• Examines six key dietary mycotoxins: aflatoxin B₁, deoxynivalenol, zearalenone, ochratoxin A, fumonisins, and patulin.
• Released under a permissive CC-BY-4.0 license, facilitating reuse and distribution.

Limitations

• The dataset is a 15.4 KB DOCX file, indicating a limited scope as a review document rather than primary data.
• Row count and column-level documentation are absent; field semantics must be inferred after download.
• The data may reflect academic review bias inherent to the figshare platform and the author's synthesis.

Provenance

Source

Alice N. Mafe via figshare.

Collection Method

Structured, hypothesis-driven narrative review.

Time Range

2016–2025

Freshness

Last updated 2026-03 17 13:04:42.

Geography

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