Pediatric Asthma-Obesity Comorbidity Circulating miRNA Profiles

Five miRNAs were consistently upregulated and two downregulated across pediatric asthma, obesity, and their comorbidity in a cross-sectional study. The dataset contains miRNA expression profiles from whole blood samples of 43 children across four clinical groups, collected by Harshita Shailesh and shared under CC-BY-4.0. Data was last updated on May 13, 2026.

Use Cases

• Identify shared miRNA biomarkers for asthma and obesity based on differential expression analysis.
• Correlate miRNA dysregulation with clinical metrics like neutrophil counts and lung function.
• Explore pathway enrichment in IL-4, IL-13, and PIP3/AKT signaling based on target gene analysis.

Strengths

• Includes data from 43 pediatric participants across four distinct clinical groups.
• Profiles were generated using the NanoString nCounter platform, a standardized method.
• Results are linked to clinical and cytokine correlation analyses.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The 22.3 KB file size suggests a very limited scope, likely summary results rather than raw expression data.

Provenance

Source

figshare

Collection Method

Whole blood samples collected from pediatric groups, with miRNA profiles assessed via NanoString nCounter platform.

Freshness

Last updated 2026-05-13 04:57:42; freshness should be verified.