Molecular Characterization of ESBL-Producing E. coli from Egyptian UTIs

Twenty ESBL-producing Escherichia coli isolates from urinary tract infections in Egypt were characterized for pathotypes, virulotypes, genotypes, and antimicrobial resistance. The dataset includes results from phylogrouping, virulence gene profiling, REP-PCR genotyping, and antibiotic susceptibility testing, along with efficacy data for selenium nanoparticles and nanocomposites. It was authored by Heba A. Ahmed and last updated in April 2026.

Use Cases

• Analyze the correlation between phylogroup classification and specific virulence genes like fimH.
• Model antimicrobial resistance patterns, such as resistance to ampicillin and cefixime, based on genotypic data.
• Compare the minimum inhibitory concentration (MIC) values of selenium nanoparticles (20 μg/mL) versus selenium nanocomposites (10 μg/mL) against ESBL-producing isolates.
• Assess bacterial strain diversity using REP-PCR genotyping results across the 20 characterized isolates.

Strengths

• Includes detailed characterization of 20 ESBL-producing E. coli isolates with multiple data facets.
• Provides concrete efficacy metrics, including specific MIC values for two novel antibacterial agents.
• Data is openly shared under a CC-BY-4.0 license, facilitating reuse.

Limitations

• Very small sample size of 20 characterized isolates from 41 clinical samples, limiting statistical power.
• Geographic scope is restricted to Egypt, which may not represent global E. coli strain diversity.
• Primary data is embedded in a DOCX document (24.0 KB), requiring extraction for computational analysis.

Provenance

Source

figshare, authored by Heba A. Ahmed.

Collection Method

Clinical isolates from hospitalized UTI patients were characterized via phylogrouping, virulence gene profiling, REP-PCR genotyping, and antibiotic susceptibility testing.

Time Range

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Freshness

Data reflects a study last updated in April 2026.

Geography

Egypt