Pipeline Embolization Device Outcomes in Small Vessel Aneurysms

Huijian Ge's multicenter study analyzes the safety and efficacy of the Pipeline Embolization Device for treating intracranial aneurysms in parent vessels under 2mm. The dataset includes 71 patients with follow-up durations of 9 months median and tracks occlusion rates and complications. This research was published on figshare in 2026.

Use Cases

• Predict delayed aneurysm occlusion (OKM grade D) using patient age, gender, and PED length from 71 patient records.
• Identify risk factors for ischemic complications by analyzing PED length and pre-existing parent vessel stenosis with logistic regression.
• Model the association between asymptomatic in-stent stenosis and pre-existing vessel stenosis using reported odds ratios.
• Analyze temporal trends in complete occlusion rates, from 52% at 1 year to 80% beyond 12 months follow-up.

Strengths

• 71 patient records from a multicenter study provide a clinical cohort.
• Reports specific statistical results, including odds ratios and confidence intervals for key predictors.
• Clear primary endpoints defined for safety (complications) and efficacy (aneurysm occlusion).

Limitations

• Small sample size of 71 patients limits statistical power for subgroup analyses.
• Retrospective study design may introduce selection bias compared to a randomized trial.
• Dataset scope is limited to a single device (PED) in a specific vessel size cohort.

Provenance

Source

Huijian Ge via figshare.

Collection Method

Multicenter retrospective study of patients who underwent PED implantation.

Time Range

Study period not specified; follow-up duration median was 9 months.

Freshness

Last updated in 2026, representing recent clinical research.

Geography

Multicenter; specific locations not provided.