N-acyl-homoserine Lactone Quorum Sensing Data from Underexplored Bacterial Lineages

A dataset from a study investigating N-acyl homoserine lactone-based quorum sensing systems in underexplored bacterial lineages, including Gram-positive Actinomycetota. The data, authored by Christy R. Handel and last updated in April 2026, was generated using custom hidden Markov models, genomic context analysis, phylogeny, and liquid chromatography-mass spectrometry. It is shared under a CC-BY-4.0 license.

Use Cases

• Comparative analysis of luxI/R homologs based on genomic context data.
• Phylogenetic studies of LuxR-family protein domain architecture divergence.
• Validation of AHL production via mass spectrometry results for novel bacterial strains.
• Investigating the association of solitary luxI genes with metabolic and redox processes in Actinomycetota.

Strengths

• Includes data from four specific bacterial strains from underexplored environments, such as a lava cave and a hypersaline mat.
• Generated using multiple methodologies: custom HMMs, LC-MRM-MS, and targeted gene disruption.
• Shared under a permissive CC-BY-4.0 license for reuse.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is small at 52.4 KB, indicating limited scope.

Provenance

Source

figshare

Collection Method

Custom hidden Markov models, genomic analysis, phylogeny, and liquid chromatography-multiple reaction monitoring-mass spectrometry.

Time Range

null

Freshness

Last updated 2026-04-20 05:20:44; freshness should be verified.

Geography

Samples from Hawai‘i and San Salvador Island, Bahamas.