Oral Squamous Cell Carcinoma Prognostic Factors for 147 Patients

A retrospective cohort of 147 oral squamous cell carcinoma patients (74 pN0, 73 pN+) who underwent curative resection and neck dissection. The dataset, authored by Shihui Shen and last updated in March 2026, integrates metabolic metrics from PET/CT scans, body composition data (L3-SMI), and pathological features. It was used to identify nodal status-specific prognostic factors for overall and progression-free survival.

Use Cases

• Train survival prediction models based on tumor metabolic burden (T-SUVmax) for node-negative patients.
• Analyze the protective effect of skeletal muscle index (L3-SMI) on survival outcomes in node-positive patients.
• Validate prognostic models using the internal bootstrap validation methodology described.
• Investigate the relationship between nodal burden (≥3 positive lymph nodes) and patient outcomes.

Strengths

• Dataset includes 147 patient records with a balanced split between pN0 (74) and pN+ (73) cases.
• Analysis includes hazard ratios and p-values for key prognostic factors like T-SUVmax and positive lymph node count.
• Findings were internally validated using bootstrap validation with 1000 repetitions.

Limitations

• Row count for the underlying data table is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is small in scale at 18.6 KB, indicating limited scope.

Provenance

Source

Shihui Shen via figshare

Collection Method

Retrospective cohort study of patients who underwent curative resection and neck dissection.

Freshness

Last updated 2026-03-17 13:06:23; freshness should be verified.