Maternal BMI and Cumulative Live Birth Outcomes in Chinese IUI Patients

3788 intrauterine insemination cycles from 1951 Chinese couples were analyzed to assess the relationship between maternal BMI and fertility success. The study, authored by Huan-Qun Zhou and last updated in June 2026, found a non-linear association where live birth probability increased up to a BMI of approximately 21.2 kg/m² before plateauing. Subgroup analyses suggested these associations may differ based on basal FSH levels and the specific gonadotropin treatment protocol used.

Use Cases

• Modeling non-linear relationships between maternal BMI and cumulative live birth rates based on the described association patterns.
• Investigating treatment outcome heterogeneity based on patient subgroups like basal FSH levels.
• Analyzing time-to-event data for fertility success using the Cox proportional hazards models mentioned in the methodology.

Strengths

• Analysis is based on a substantial sample of 3788 treatment cycles from 1951 couples.
• The study employs multiple statistical models (GLM, GEE, GAM, Cox) to characterize associations from different angles.
• Results include specific clinical thresholds, such as a BMI of approximately 21.2 kg/m², where the association pattern changes.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The data reflects a specific patient population (Chinese women undergoing IUI), which may limit generalizability.

Provenance

Source

figshare

Collection Method

Retrospective analysis of clinical data, as stated in the description.

Freshness

Last updated 2026-06-03 04:26:40; freshness should be verified.

Geography

China (inferred from the patient population described).