Optimal Exercise Dosage for Menopausal Depression from Network Meta-Analysis

A 2026 systematic review and network meta-analysis by Hongyu Wang synthesizes evidence from 23 randomized controlled trials. It compares optimal dose ranges for four exercise types—aerobic, multi-mode, stretching, and mind–body—to improve depressive symptoms in climacteric women. The analysis uses Bayesian network meta-regression on data from PubMed, Cochrane Library, Embase, and Web of Science up to September 2025.

Use Cases

• Compare efficacy rankings (SUCRA scores) of aerobic, multi-mode, stretching, and mind–body exercises for depression reduction.
• Model dose-response relationships using reported MET-min/week ranges (e.g., 600–1,100 for aerobic) to identify optimal exercise dosage.
• Analyze the association between intervention parameters (3 sessions/week, 12-week duration) and observed favorable outcome ranges.
• Identify research gaps by examining data limitations for high-dose mind–body exercise (>1,500 MET-min/week).

Strengths

• Evidence synthesized from 23 randomized controlled trials.
• Uses Bayesian network meta-regression (MBNMA) for dose-response modeling.
• Registered on PROSPERO (CRD420251162965) following systematic review protocol.

Limitations

• Limited data for high-dose mind–body exercise (>1,500 MET-min/week).
• Small dataset scope (321.2 KB), containing a single review document without underlying trial data.
• Findings are specific to climacteric women and may not generalize to other populations.

Provenance

Source

figshare, authored by Hongyu Wang.

Collection Method

Systematic review and network meta-analysis of RCTs from PubMed, Cochrane Library, Embase, and Web of Science.

Time Range

Literature search from database inception to September 2025.

Freshness

Last updated April 2026, with literature search up to September 2025.

Geography

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