Mouse Study Data on Allium mongolicum Polysaccharide and Intestinal Injury

A 31.5 KB document contains results from a biological experiment investigating Allium mongolicum Regel polysaccharides (AMRP). The study used 36 specific pathogen-free mice across three treatment groups to analyze effects on intestinal injury, inflammation, and endoplasmic reticulum stress pathways. Author Xiaoyu Niu published the findings on figshare in March 2026.

Use Cases

• Analyze the relationship between treatment groups (CON, DQ, AMRP+DQ) and measured outcomes like thymus and spleen indices.
• Model the effect of AMRP supplementation on serum levels of pro-inflammatory and anti-inflammatory cytokines.
• Investigate the suppression of key ERS pathway factors (PERK, ATF4, CHOP) in intestinal tissues across experimental groups.
• Correlate the optimized extraction conditions (25% papain, 4.5h hydrolysis, 63°C) with the observed biological efficacy of AMRP.

Strengths

• Data is derived from a controlled in vivo experiment with 36 mice across three defined treatment groups.
• Study measures multiple biological endpoints, including organ indices, serum cytokines, and tissue pathway expression.
• Document includes specific numerical results from the optimization of polysaccharide extraction conditions.

Limitations

• The dataset is extremely small (31.5 KB), contained within a single document, limiting analytical scope.
• Raw experimental data tables or columnar data are not provided, only summarized results in narrative form.
• Sample size is limited to 36 mice, which may constrain statistical power for subgroup analyses.

Provenance

Source

figshare, author Xiaoyu Niu.

Collection Method

Controlled laboratory experiment involving animal subjects and biochemical analysis.

Time Range

Covers a 28-day experimental period (7-day pre-feeding, 21-day trial).

Freshness

Last updated March 2026.

Geography

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