Ornithine Decarboxylase Role in Wuding Chicken Ovarian Regression

Wuding chickens, a breed exhibiting pronounced broodiness, were employed to elucidate the role of Ornithine Decarboxylase (ODC) in follicular maturation. The dataset, authored by Xinyu Ma and last updated in April 2026, contains a comprehensive analysis of ODC expression across the hypothalamic–pituitary-gonadal (HPG) axis and its effects on granulosa cell physiology. It is a 1.3 MB document shared under a CC-BY-4.0 license on figshare.

Use Cases

• Study the molecular regulation of the laying-to-broody transition based on ODC expression analysis across the HPG axis.
• Investigate granulosa cell cycle progression and apoptosis based on the described roles of ODC, c-MYC, cyclins, BCL2, and Caspase-3.
• Analyze steroidogenic capacity in ovarian follicles based on the coordinated regulation of key genes like FSHR and STAR.
• Examine polyamine metabolism in cell physiology based on the modulation of SAT1 and PAOX gene expression.

Strengths

• Dataset is shared under a permissive CC-BY-4.0 license, allowing for broad reuse.
• The description provides a detailed biological context and mechanistic findings from the associated study.
• File size is 1.3 MB, indicating a manageable download.

Limitations

• The primary data format is a DOCX document, which may require extraction or manual parsing for computational analysis.
• Row count and column-level documentation are absent, limiting suitability assessment for structured analysis.
• The dataset's scale is small (1.3 MB), which may limit the amount of raw or tabular data present.

Provenance

Source

figshare

Collection Method

Likely contains experimental data and analysis from a study on Wuding chickens, including gene expression analysis and primary cell culture assays.

Freshness

Last updated 2026-04-21 10:03:28; freshness should be verified.

Geography

Study focuses on Wuding chickens, a specific breed.