Kodamaea Ohmeri Fungemia Outbreak in a Neonatal ICU

A case series documents a clonal outbreak of Kodamaea ohmeri fungemia in five neonates within a single hospital's NICU over two months. The dataset includes clinical, epidemiological, and microbiological data for the patients, alongside a systematic review of 38 historical cases. Author Kehong Lou published this research on figshare in April 2026.

Use Cases

• Analyze risk factors like indwelling catheters and broad-spectrum antibiotic use across the five outbreak cases and 38 historical cases.
• Compare antifungal susceptibility profiles, specifically fluconazole MICs (4–8 μg/mL) versus echinocandin and amphotericin B MICs, for the outbreak isolates.
• Study clonal transmission evidence using the identical microsatellite genotypes reported across three polymorphic loci for seven isolates.
• Review clinical outcomes, such as the 100% survival rate in this outbreak versus the 32% mortality rate identified in the literature review.

Strengths

• Includes detailed microbiological characterization (MALDI-TOF MS, antifungal susceptibility testing, microsatellite genotyping) for outbreak confirmation.
• Provides a systematic literature review synthesizing data from 38 total patients with K. ohmeri bloodstream infections.
• Reports specific clinical data points for five neonates, including median age (1 month), interventions, and outcomes.

Limitations

• Extremely small primary sample size of only five patient cases from a single hospital.
• No raw, structured data tables are provided; all information is contained within a narrative research document.
• Geographic scope is limited to one tertiary hospital in China, limiting generalizability.

Provenance

Source

figshare, authored by Kehong Lou.

Collection Method

Retrospective case series analysis combined with a systematic literature review.

Time Range

Outbreak occurred within a 2-month period; literature review covers historical cases up to the publication date.

Freshness

Last updated April 2026, representing recent research.

Geography

Tertiary general hospital in China.