Bacillus Cereus Pathogenesis Data from Galleria Mellonella Infection Model

Jessica Minnaard's dataset, published on figshare in April 2026, contains results from a study using the insect Galleria mellonella as an infection model to assess the pathogenicity of two human-derived Bacillus cereus strains. The 77.6 KB Excel file likely includes data on larval survival, bacterial persistence, immune activation markers, and spore formation from infection assays combined with genomic comparisons. The analysis reveals differences in virulence factors and immune responses between the two strains.

Use Cases

• Compare virulence between bacterial strains based on dose-dependent mortality and persistence data.
• Analyze correlations between specific genomic factors and host immune responses like phenoloxidase activity.
• Model bacterial colonization dynamics based on spore formation and persistence timeframes.
• Study conserved virulence mechanisms across hosts based on the core set of shared toxin genes.

Strengths

• Data is derived from a controlled experimental model combining infection assays with genomic analysis.
• Includes specific, comparable results for two distinct bacterial strains (T1 and B10502).
• Published under a permissive CC-BY-4.0 license for reuse.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset's 77.6 KB size indicates a very limited scope, likely containing summary or processed results rather than raw experimental data.

Provenance

Source

Jessica Minnaard via figshare.

Collection Method

Generated from larval infection assays and whole-genome phylogenetic analysis of two Bacillus cereus strains.

Time Range

Temporal coverage of the experimental study is not specified.

Freshness

Last updated 2026-04-15 05:22:59; freshness should be verified.

Geography

Spatial coverage is not specified.