Research Paper on PFOS Exposure and Glaucoma Risk via FABP4

A 49.0 KB document presents research linking perfluorooctanesulfonic acid (PFOS) to primary open-angle glaucoma. The study uses NHANES and GBD data, network toxicology, and in vitro experiments to propose a FABP4-mediated mechanism. Authored by Jiangpeng Lin and last updated in May 2026, the document is shared under a CC-BY-4.0 license.

Use Cases

• Literature review on environmental risk factors for glaucoma based on the described research findings.
• Methodological reference for integrating NHANES and GBD data with bioinformatic analysis.
• Investigation of FABP4 as a biomarker for chemical-induced cellular senescence.
• Toxicological risk assessment for PFOS exposure based on the proposed molecular pathway.

Strengths

• Document is openly licensed (CC-BY-4.0) for reuse.
• Research integrates multiple data sources (NHANES, GBD) and methods (machine learning, molecular docking).

Limitations

• The dataset is a single 49.0 KB document, not a structured data collection.
• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.

Provenance

Source

Author: Jiangpeng Lin. Platform: figshare.

Collection Method

Research paper describing analysis of cross-sectional data from NHANES and GBD databases, combined with in vitro experiments.

Freshness

Last updated 2026-05-11 22:03:10; freshness should be verified.