Placental Biology Review Linking Genetics, Epigenetics, and Social Determinants

A 13.3 KB Excel file published by Viviane Schuch on figshare in April 2026. It synthesizes evidence on how placental biology integrates genetic variation, epigenetic regulation, immune processes, and social context to shape pregnancy outcomes, with a focus on health inequities affecting Black and African American women.

Use Cases

• Reviewing evidence on placental dysfunction and immune dysregulation based on the synthesized literature.
• Analyzing the role of genetic variation and epigenetic mechanisms in pregnancy outcomes based on the described biological pathways.
• Investigating the impact of socioeconomic and environmental exposures on fetal development based on the described placental epigenetic links.
• Evaluating the constraints of ancestry representation in pregnancy genomic research based on the survey of genome-wide association studies.

Strengths

• File size is precisely 13.3 KB, indicating a concise dataset.
• License is explicitly CC-BY-4.0, allowing open reuse.
• Last updated date is April 15, 2026, indicating recent availability.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is described as sparse and fragmented, suggesting potential gaps in coverage.

Provenance

Source

figshare

Collection Method

Likely a synthesized review or compilation of published evidence.

Freshness

Last updated 2026-04-15 05:46:13

Geography

Focus on United States, particularly Black and African American populations.