BNT162b2 Vaccine Proteomic Changes: Longitudinal Plasma Protein Levels in Qatar

354 plasma proteins were quantified longitudinally in 70 healthy individuals using Olink technology. The data, published by Sana Bentebbal on figshare, captures protein levels before, 3 months, and 6 months after a third BNT162b2 mRNA vaccine dose. It includes results for infection-naïve and previously infected individuals.

Use Cases

• Analyze sustained protein changes like PARP-1 and MMP-7 based on longitudinal proteomic profiling
• Compare vaccine-induced proteomic responses between infection-naïve and previously infected individuals
• Investigate temporal dynamics of inflammatory proteins based on 3- and 6-month post-booster measurements

Strengths

• Quantifies 354 unique plasma proteins per sample
• Includes longitudinal data from 70 individuals across three time points
• Provides fold-change (FC) and statistical significance (p, pFDR) values for key proteins

Limitations

• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment
• Data is limited to a cohort of 70 individuals from Qatar

Provenance

Source

figshare

Collection Method

Plasma levels quantified using Olink technology in a longitudinal study.

Time Range

Data collected before, 3 months, and 6 months post-booster vaccination.

Freshness

Last updated 2026-04-24 05:37:09; freshness should be verified

Geography

Qatar