Pre-existing Iron Deficiency Anemia and Long-Term Risk of Recurrent Acute Kidney Injury

13,002 propensity-matched individuals from a retrospective cohort study using the TriNetX database (2010–2024). This dataset examines associations between pre-existing iron deficiency anemia and recurrent acute kidney injury, renal function decline, and other outcomes in ICU survivors. The research was authored by Kuo-Chuan Hung and published on figshare under a CC-BY-4.0 license.

Use Cases

• Analyze the association between pre-existing iron deficiency anemia and recurrent acute kidney injury risk based on hazard ratios.
• Study the relationship between anemia and accelerated renal function decline based on estimated glomerular filtration rate outcomes.
• Investigate secondary outcomes like major adverse cardiovascular events and mortality in a matched cohort.
• Validate observational findings for prospective clinical investigations based on the study's methodology.

Strengths

• The dataset is derived from a propensity-matched cohort of 13,002 individuals per group.
• The study employs a 90-day landmark approach to minimize immortal-time bias.
• Follow-up extends to 3-5 years, allowing for long-term outcome assessment.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The observational design cannot establish causal relationships, as noted in the conclusion.

Provenance

Source

TriNetX database

Collection Method

Propensity score-matched retrospective cohort study

Time Range

2010–2024

Freshness

Last updated 2026-05-05 04:10:05; freshness should be verified.