Predicted No-Effect Concentrations for 17 Antifungal Compounds

A 2026 study by D. Gil calculates predicted no-effect concentrations (PNECs) for 17 antifungal compounds, using Candida albicans as a model organism. The data, derived from a systematic review of 122 articles, aims to inform regulation of antifungal release in wastewater and agricultural settings to mitigate resistance risks.

Use Cases

• Prioritize the 17 listed antifungal compounds for environmental regulation based on their calculated PNEC values.
• Compare PNEC values for different antifungals to determine acceptable concentration levels in wastewater effluents.
• Use the PNEC data, derived from Candida albicans models, to assess potential environmental risks for antifungal resistance development.
• Integrate the systematic review findings from 122 articles into environmental impact assessments for antifungal pollution.

Strengths

• Data is based on a systematic review of 122 scientific articles, providing a consolidated evidence base.
• Provides calculated PNEC values for 17 specific antifungal compounds, offering actionable regulatory metrics.
• The dataset is recent, with a last update in March 2026, reflecting current research concerns.

Limitations

• The dataset is small in file size (604.9 KB), indicating limited scope and likely a summary table rather than raw experimental data.
• PNEC calculations are based on a single model organism (Candida albicans), which may not represent effects on all environmental fungi.
• The specific row count and column structure are unknown, limiting understanding of the dataset's granularity and features.

Provenance

Source

D. Gil via figshare.

Collection Method

Systematic literature review following PRISMA-ScR guidelines, analyzing 122 articles.

Time Range

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Freshness

Last updated March 2026.

Geography

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