Predictors of Target Lesion Revascularization After Paclitaxel-Coated Balloon Angioplasty

A retrospective analysis of a prospective PCI registry study evaluated 112 patients (129 lesions) who underwent successful paclitaxel-coated balloon angioplasty for de novo coronary lesions. The study identified calcified lesions as an independent predictor of target lesion revascularization (TLR) over a median angiographic follow-up of 139 days. It was conducted at a single center in Indonesia between January 2020 and December 2024.

Use Cases

• Analyze the association between calcified lesions and the incidence of target lesion revascularization (TLR) using adjusted odds ratios.
• Evaluate the relationship between baseline clinical characteristics and secondary endpoints like major adverse cardiovascular events (MACE) at 12 months.
• Investigate procedural factors such as balloon inflation time and maximal inflation pressure for their impact on TLR outcomes.
• Assess the role of intravascular imaging utilization and predilation procedures in patient outcomes following drug-coated balloon angioplasty.

Strengths

• Clinical data from 112 patients and 129 specific lesions provides a focused cohort for analysis.
• Study includes a 12-month follow-up period for tracking major adverse cardiovascular events (MACE).
• Clear temporal coverage from January 2020 to December 2024 for the procedural data.

Limitations

• Small sample size of 112 patients may limit the statistical power for detecting all predictor variables.
• Single-center study design from Indonesia may limit the generalizability of findings to other populations.
• Data is presented in a DOCX document (670.3 KB), not a structured tabular format, requiring extraction for computational analysis.

Provenance

Source

Tommy Suharjo via figshare.

Collection Method

Single-center retrospective analysis of a prospective percutaneous coronary intervention (PCI) registry study.

Time Range

January 2020 to December 2024 for procedures, with a 12-month clinical follow-up.

Freshness

Data covers procedures through December 2024, with the record last updated in March 2026.

Geography

Single-center study conducted in Indonesia.