Prenatal Stress Effects on Adult Stress Recovery in Rodents

Branden G. Verosky's research examines how prenatal stress alters behavioral and transcriptional responses to repeated adult stress in rodent offspring. The dataset likely contains results from a 2x2 factorial design study measuring corticosterone levels, anxiety-like behavior, social behavior, and gene expression across four brain regions. The file was last updated on May 13, 2026, and is shared under a CC-BY-4.0 license.

Use Cases

• Modeling long-term effects of prenatal stress based on behavioral and endocrine endpoints.
• Analyzing sex-specific gene regulation patterns during stress recovery phases.
• Investigating region-specific transcriptional responses in stress-regulatory brain circuits.
• Studying the interaction between early-life and adult-life stressors on psychopathology risk.

Strengths

• Data is derived from a controlled 2x2 factorial experimental design.
• Includes multi-modal endpoints: behavioral, endocrine, and transcriptional measurements.
• Examines four key brain regions: prefrontal cortex, hippocampus, amygdala, and hypothalamus.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The dataset is very small at 21.3 KB, indicating limited scope.

Provenance

Source

Branden G. Verosky

Collection Method

Experimental study involving prenatal restraint stress in pregnant rodent dams and subsequent adult restraint stress in offspring.

Freshness

Last updated 2026-05-13 04:41:20; freshness should be verified.