Prior Copper IUD Use and IVF/ICSI Outcomes from 62,422 Embryo Transfer Cycles

62,422 embryo transfer cycles from a retrospective cohort study conducted between September 2008 and December 2023. The dataset, authored by Wenjie Huang and shared on figshare, compares reproductive and neonatal outcomes for women with and without a history of copper intrauterine device use. It includes 3,151 cycles with prior Cu-IUD exposure and 59,271 cycles without any IUD history.

Use Cases

• Assessing the association between prior contraceptive use and live birth rates based on the primary outcome measure.
• Comparing biochemical pregnancy, clinical pregnancy, and miscarriage rates between patient cohorts as described in the secondary outcomes.
• Evaluating the effect of patient age, AMH, or BMI on outcomes through stratified analyses mentioned in the results.
• Applying propensity score matching methodology to balance baseline characteristics in observational clinical data.

Strengths

• Large sample size of 62,422 embryo transfer cycles, including 27,692 fresh and 34,730 frozen–thawed cycles.
• Study period spans over 15 years, from September 2008 to December 2023.
• Uses propensity score matching (1:2) to control for confounding variables in the analysis.
• Explicitly reports live birth rates (e.g., 28.0% vs. 27.7% for fresh cycles) and adjusted risk ratios with confidence intervals.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count for the underlying matched dataset is unknown, which may limit suitability assessment.
• Data may reflect temporal or institutional bias inherent to the single-study source on figshare.

Provenance

Source

Wenjie Huang via figshare.

Collection Method

Retrospective cohort study of clinical records.

Time Range

September 2008 to December 2023.

Freshness

Last updated 2026-04-30 05:41:28; freshness should be verified.