Justine Smout's dataset from 2026 contains experimental results from a microbiota-humanized mouse model. The data likely includes measurements of immune cell populations and bacterial clearance from mice colonized with fecal samples from probiotic- or placebo-treated preterm infants in the PRIMAL trial. Findings demonstrate how probiotic-driven shifts in microbial communities can attenuate immune cell development and alter infection outcomes.
Use Cases
- Modeling the relationship between probiotic-conditioned microbiota and innate immune cell populations based on the described experimental results.
- Analyzing the impact of vertically transmitted human-derived microbiota on bacterial clearance after pathogen challenge.
- Investigating tissue-specific immune responses (colon, small intestine, spleen) to microbial shifts as described in the study.
Strengths
- Data is associated with a specific clinical trial (PRIMAL) and a described experimental mouse model.
- Dataset is openly licensed under CC-BY-4.0, permitting reuse with attribution.
- File is available in the widely compatible XLSX format.
Limitations
- Row count and specific column definitions are unknown, requiring manual inspection after download.
- The dataset is very small at 90.5 KB, indicating limited scope or summary-level data.
Provenance
- Source
- Justine Smout, via figshare.
- Collection Method
- Likely derived from laboratory experiments colonizing germ-free mice with fecal samples from a clinical trial.
- Freshness
- Last updated 2026-04-20 04:13:36.