Prognostic Significance of Post-Treatment Nodal Status in Lung Cancer

A systematic review and meta-analysis evaluating the association between pathological nodal status (ypN) and survival outcomes after neoadjuvant chemoimmunotherapy for resectable non-small cell lung cancer. The analysis includes two studies for overall survival and disease-free survival, with pooled hazard ratios calculated. The work was authored by Huan Shao and published on figshare in May 2026.

Use Cases

• Evaluating the prognostic value of post-treatment nodal status based on hazard ratios for survival
• Comparing survival outcomes between different pathological response classifications
• Supporting clinical decision-making for neoadjuvant treatment strategies

Strengths

• Follows PRISMA 2020 guidelines for systematic review methodology
• Provides pooled hazard ratios with confidence intervals and statistical significance (P < 0.00001 for OS)
• Includes sensitivity analyses showing consistent results

Limitations

• Row count is unknown, which may limit suitability assessment
• Column-level documentation is absent; field semantics must be inferred after download
• The meta-analysis includes only two retrospective studies, as noted in the conclusions

Provenance

Source

figshare

Collection Method

Systematic review and meta-analysis of studies from PubMed, Web of Science, Scopus, Embase, and Cochrane Library.

Time Range

Studies searched from inception to February 26, 2026.

Freshness

Last updated 2026-05-22 04:38:02