Table 1_Protocol for a systematic review and meta-analysis of the relationship between opi

Yulia Shatalov's protocol outlines the planned methodology for a systematic review and meta-analysis of dopaminergic neuroimaging findings in individuals with opioid use disorder. The protocol was registered to PROSPERO (CRD420251229301) and is scheduled for an update on 2026-04-30. It describes a search of databases including PubMed, Scopus, Web of Science, Google Scholar, and Embase for peer-reviewed studies using PET or SPECT imaging.

Use Cases

• Planning a systematic review based on the described search strategy and eligibility criteria for databases like PubMed and Scopus.
• Designing a meta-analysis of dopaminergic measures such as D2/D3 receptor availability using the random-effects model described.
• Assessing methodological quality in neuroimaging studies of opioid use disorder based on the outlined reviewer screening process.
• Investigating the clinical relevance of dopaminergic markers for informing novel pharmacotherapies for OUD as discussed in the protocol's rationale.

Strengths

• The protocol is registered with a PROSPERO ID (CRD420251229301), indicating a formal review plan.
• It specifies a search across five major academic databases (PubMed, Scopus, Web of Science, Google Scholar, Embase).
• The methodology includes a two-stage screening process by independent reviewers and plans for sensitivity analyses.

Limitations

• The dataset is a 679.6 KB DOCX protocol document, not the resulting data or analysis, which limits its immediate use for modeling.
• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.

Provenance

Source

Yulia Shatalov via figshare

Collection Method

Document outlining planned methodology for a literature synthesis.

Freshness

Last updated 2026-04-30 11:45:17; freshness should be verified.